Long-term health-related quality of life after surgery in patients with chronic thromboembolic pulmonary hypertension
O Kamenskaya, A Klinkova, A Chernyavskiy… - Quality of Life …, 2020 - Springer
O Kamenskaya, A Klinkova, A Chernyavskiy, VV Lomivorotov, A Edemskiy, V Shmyrev
Quality of Life Research, 2020•SpringerPurpose To assess the dynamic of various health-related quality of life (HRQoL) parameters
3 years after pulmonary thromboendarterectomy (PTE), and to identify factors affecting
HRQoL parameters in patients with chronic thromboembolic pulmonary hypertension
(CTEPH) in the long-term follow-up after surgery. Methods This prospective cohort study
included 128 patients with CTEPH before and after the PTE (3 year follow-up). The HRQoL
was examined using the Short-Form 36 Health Survey Questionnaire (SF-36). Results In …
3 years after pulmonary thromboendarterectomy (PTE), and to identify factors affecting
HRQoL parameters in patients with chronic thromboembolic pulmonary hypertension
(CTEPH) in the long-term follow-up after surgery. Methods This prospective cohort study
included 128 patients with CTEPH before and after the PTE (3 year follow-up). The HRQoL
was examined using the Short-Form 36 Health Survey Questionnaire (SF-36). Results In …
Purpose
To assess the dynamic of various health-related quality of life (HRQoL) parameters 3 years after pulmonary thromboendarterectomy (PTE), and to identify factors affecting HRQoL parameters in patients with chronic thromboembolic pulmonary hypertension (CTEPH) in the long-term follow-up after surgery.
Methods
This prospective cohort study included 128 patients with CTEPH before and after the PTE (3 year follow-up). The HRQoL was examined using the Short-Form 36 Health Survey Questionnaire (SF-36).
Results
In patients with CTEPH 3 years after PTE, a significant improvement in all the HRQoL parameters. The summary indicators of the physical and mental components of health remained at the same level as 1 year after the PTE and did not exceed 50 points. The residual pulmonary hypertension was a leading factor limiting parameters of physical and mental health 3 years after a PTE. In addition, the parameters of physical activity were adversely affected by age and the age-adjusted Charlson Comorbidity Index.
Conclusions
In the study group of patients with CTEPH, PTE contributes to a significant improvement in all HRQoL parameters, which observed both 1 year and 3 years after surgery. The leading factor adversely affecting the physical and emotional components of health in the long-term period after PTE was residual pulmonary hypertension recorded in the early postoperative period. In addition, some physical HRQoL parameters are affected by age and age-adjusted Charlson Comorbidity Index.
Springer
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